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Medical Definition of Upper motor neuron
1. Clinical term indicating those neuron's of the motor cortex that contribute to the formation of the pyramidal or corticospinal and corticobulbar tracts, as distinguished from the lower motor neuron's innervating the skeletal muscles. Although not motor neuron's in the strict sense, these cortical neuron's became colloquially classified as motor neuron's because their stimulation produces movement and their destruction causes severe disorders of movement. See: motor neuron, motor cortex. (05 Mar 2000)