Medical Definition of Ubiquitin-protein ligase

1. Consists of 3 enzymes; e1 is ubiquitin activating enzyme; e2 transfers activated ubiquitin as an enzyme-ubiquitin thiol ester to e3, which transfers ubiquitin to an intracellular protein; e1 forms both an enzyme-bound cooh-terminal ubiquitin thiolester and a cooh-terminal ubiquitin-adenylatte; ube1y is putative y function in spermatogonial proliferation; ube1x and ube1y encode the e1 enzyme Registry number: EC 6.3.2.19 Synonym: ubiquitin-protein ligase system, ubiquitin-protein-lysine n-omega-ligase, ubiquitin-activating enzyme, ubiquitin-activating enzyme e1, ubiquitination activating enzyme e1, ube1 gene product, rsp5 ubiquitin-protein ligase, npi1 protein, ube1y gene product, ube1x gene product, ikappab-ubiquitin ligase (26 Jun 1999)

Lexicographical Neighbors of Ubiquitin-protein Ligase

ubiquinol
ubiquinol-cytochrome-c reductase
ubiquinols
ubiquinone
ubiquinone-10
ubiquinone-6
ubiquinones
ubiquitarian
ubiquitaries
ubiquitariness
ubiquitary
ubiquities
ubiquitin
ubiquitin-Nalpha-protein hydrolase
ubiquitin-calmodulin ligase
ubiquitin carrier protein kinase
ubiquitin thiolesterase
ubiquitinate
ubiquitinated
ubiquitinates
ubiquitinating
ubiquitination
ubiquitinations
ubiquitinoylation
ubiquitinylate
ubiquitinylated
ubiquitinylates
ubiquitinylating
ubiquitinylation

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