|
Medical Definition of Two-dimensional chromatography
1. Paper chromatography in which a spot, located originally in one corner of a sheet, is developed in one direction along one side of the sheet, after which the sheet is rotated 90° and developed, with another solvent, in the new direction; the resultant spots are thus spread over the entire paper, giving a "map" or "fingerprint." Also generalised to include chromatography followed by electrophoresis (or vice versa), column chromatography followed by paper chromatography, etc. (05 Mar 2000)