Lexic.us

Definition of Tumor necrosis factor

1. Noun. A proinflammatory cytokine that is produced by white blood cells (monocytes and macrophages); has an antineoplastic effect but causes inflammation (as in rheumatoid arthritis).

Definition of Tumor necrosis factor

1. Noun. (medicine) Any of several polypeptide hormones, produced by macrophages, that can destroy some cancer cells ¹

¹ Source: wiktionary.com

Medical Definition of Tumor necrosis factor

1. Originally described as a tumour inhibiting factor in the blood of animals exposed to bacterial lipopolysaccharide or Bacille Calmette-Guerin. Preferentially kills tumour cells in vivo and in vitro, causes necrosis of certain transplanted tumours in mice and inhibits experimental metastases. Human Tumour Necrosis factor alpha is a protein of 157 amino acids and has a wide range of pro inflammatory actions. Usually considered a cytokine. Synonym: cachectin. Acronym: TNF (13 Nov 1997)

Lexicographical Neighbors of Tumor Necrosis Factor

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