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Medical Definition of Tryptophan pyrrolase
1. An oxidoreductase catalyzing the reaction of l-tryptophan and O2 to produce l-N-formylkynurenine; an adaptive enzyme, the level (in the liver) being controlled by adrenal hormones; a step in tryptophan catabolism; also, a step in the synthesis of NAD+ from tryptophan. Synonym: pyrrolase, tryptophan oxygenase, tryptophan pyrrolase, tryptophanase. (05 Mar 2000)