Definition of Tropomyosin
1. [n -S]
Medical Definition of Tropomyosin
1.
Protein (66 kD) associated with actin filaments both in cytoplasm and (in association with troponin) in the thin filament of striated muscle.
Composed of two elongated _ helical chains (each about 33 kD), 40 nm long, 2 nm diameter. Each chain has six or seven similar domains and interacts with as many G actin molecules as there are domains.
Not only does the binding of tropomyosin stabilise the F actin, but the association with troponin in striated muscle is important in control by calcium ions.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
Lexicographical Neighbors of Tropomyosin
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