Lexic.us

¹ Source: wiktionary.com

Definition of Transfection

1. [n -S]

Medical Definition of Transfection

1. The introduction of DNA into a recipient eukaryote cell and its subsequent integration into the recipient cells chromosomal DNA. Usually accomplished using DNA precipitated with calcium ions though a variety of other methods can be used (e.g. Electroporation). Only about 1% of cultured cells are normally transfected. Transfection is analogous to bacterial transformation but in eukaryotes transformation is used to describe the changes in cultured cells caused by tumour viruses. (17 Mar 1998)

Lexicographical Neighbors of Transfection

Literary usage of Transfection

Below you will find example usage of this term as found in modern and/or classical literature:

1. Molecular Neurobiology: Proceedings of the 2nd NIMH Conference by Steven Zalcman (1995)
"... Phorbol Ester-Induced Modulation of Brain KV3.1 Expressed by Stable transfection of Human Embryonic Kidney Cells SD Critz, HS Lopez, BA Wible, ..."

2. Smokeless Tobacco Or Health: An International Perspective by DIANE Publishing Company (1993)
"transfection DNA transfection was performed by the calcium phosphate precipita- Assays ... Positive control DNA for transfection assays was extracted from ..."

3. Reviews in Environmental Health (1998): Toxicological Defense Mechanics edited by Gary E. R. Hook, George W. Lucier (2000)
"Using antioxidants, transient transfection assays using an IL-8 promoter construct linked to a Chloram- phenicol acetyltransferase reporter gene revealed ..."

4. Gene Expression in Horticultural Crops: Bibliography January 1991-October 1992 by Robert D. Warmbrodt (1995)
"... of analysis (30 min) and precise means of detecting acetylated products at the nanomolar level, enabling quantification at very low transfection rates. ..."

5. Transgenic Animals: Bibliography January 1991-February 1994 by Raymond Dobert (1996)
"Language: English Descriptors: Chickens; Avian oncovirus; Rous sarcoma virus; Structural genes; Receptors; Loci; transfection; Gene transfer; ..."

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