Lexic.us

Definition of Tophus

1. Noun. A deposit of urates around a joint or in the external ear; diagnostic of advanced or chronic gout.

Definition of Tophus

1. n. One of the mineral concretions about the joints, and in other situations, occurring chiefly in gouty persons. They consist usually of urate of sodium; when occurring in the internal organs they are also composed of phosphate of calcium.

Definition of Tophus

1. Noun. (medicine) A deposit of monosodium urate crystals in the body, caused by high levels of uric acid in the blood. ¹

¹ Source: wiktionary.com

Definition of Tophus

1. a deposit of urates in the tissue around a joint [n -PHI]

Medical Definition of Tophus

1. A chalky deposit of sodium urate occurring in gout, tophi form most often around joints in cartilage, bone, bursae and subcutaneous tissue and in the external ear, producing a chronic foreign body inflammatory response. Origin: L. = porous stone This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

Lexicographical Neighbors of Tophus

Literary usage of Tophus

Below you will find example usage of this term as found in modern and/or classical literature:

1. Clinical Lectures on the Diseases of Old Age by Jean Martin Charcot, Alfred Lebbeus Loomis (1881)
"... of Urate of Soda occupy by Preference those Tissues Deprived of Vessels—Condition of the Synovia] Membranes and the Ligaments—tophus (Chalk-Stone); ..."

2. Clinical Lectures on the Diseases of Old Age by Jean Martin Charcot, Alfred Lebbeus Loomis (1881)
"... occupy by Preference those Tissues Deprived of Vessels — Condition of the Synovial Membranes and the Ligaments — tophus (Chalk-Stone) ; its Composition ..."

3. The Natural History of Pliny by Pliny, John Bostock, Henry Thomas Riley (1857)
"tophus. . Among the multitude of stones which still remain unde- scribed, there is tophus ;32 a material totally unsuited for building purposes, ..."

4. Travels in Northern Greece. by William Martin Leake (1835)
"... Pale—Population and productions of Kefalonia— Proni, Asms, Atella, tophus, Heraclia, ... tophus ..."

5. Clinical Lectures on Senile and Chronic Diseases by Jean Martin Charcot (1881)
"Seat of election in gout ; joints that are attacked.—Chalky concretions around joints.—Concretions in the substance of the skin.—tophus in the external ear. ..."

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