Medical Definition of Tissue-inhibitor of metalloproteinase-1
1.
A member of the family of tissue inhibitor of metalloproteinases. It is a n-glycosylated protein, molecular weight 28 kD, produced by a vast range of cell types and found in a variety of tissues and body fluids. It has been shown to suppress metastasis and inhibit tumour invasion in vitro.
Pharmacological action: antineoplastic agent, protease inhibitors.
(12 Dec 1998)
Lexicographical Neighbors of Tissue-inhibitor Of Metalloproteinase-1
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