¹ Source: wiktionary.com
Medical Definition of Thrombospondins
1. A family of related, adhesive glycoproteins which are synthesised, secreted, and incorporated into the extracellular matrix of a variety of cells, including alpha granules of platelets following thrombin activation and endothelial cells. They interact with a number of blood coagulation factors and anticoagulant factors. Five distinct forms have been identified, thrombospondin 1, -2, -3, -4, and cartilage oligomeric matrix protein (comp). They are involved in cell adhesion, platelet aggregation, cell proliferation, angiogenesis, tumour metastasis, vascular smooth muscle growth, and tissue repair. (12 Dec 1998)
Lexicographical Neighbors of Thrombospondins
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