Medical Definition of Thrombocytopenia purpura
1.
In severe thrombocytopenia, bleeding into skin leads to small petechial haemorrhages.
Primary thrombocytopenia purpura is of unknown cause but results from an autoimmune mechanism that causes platelet destruction.
Secondary thrombocytopenic purpura may result from drug-induced type II hypersensitivity in which platelets coated with antibody to the drug (which is acting as a hapten) are destroyed in a complement mediated reaction. It can also follow a viral upper respiratory infection and may be seen in association with lupus.
(15 Oct 1997)
Lexicographical Neighbors of Thrombocytopenia Purpura
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