Lexic.us

Definition of Spironolactone

1. Noun. A synthetic corticosteroid (trade name Aldactone) used to treat hypertension.

Definition of Spironolactone

1. Noun. A particular diuretic and antiandrogen. ¹

¹ Source: wiktionary.com

Medical Definition of Spironolactone

1. Aldosterone antagonist: diuretic, used to treat low renin hypertension and Conn's syndrome (in which there is overproduction of aldesterone). This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

Lexicographical Neighbors of Spironolactone

Literary usage of Spironolactone

Below you will find example usage of this term as found in modern and/or classical literature:

1. Stress, Gender, and Alcohol-Seeking Behavior edited by Walter A. Hunt, Sam Zakhari (1996)
"At these times the MR antagonist spironolactone was an effective anticon- vulsant. When CORT levels were low, as during the first hours of the light cycle, ..."

2. 5th Report Of The Joint National Committee On Detection, Evaluation, And by DIANE Publishing Company (2004)
"... Bumetanide Ethacrynic acid Furosemide Potassium sparing: Amiloride spironolactone Triamterene 0.5-5 25.0 -100 20.0-320 (Once/day unless otherwise noted) ..."

3. Carcinogenic Potency Database, Endocrine Disruptors edited by Lois Swirsky Gold (2000)
"... Progesterone in oil for injection Antiandrogens spironolactone (receptor antagonist and synthesis inhibitor) Flutamide (receptor antagonist) Finasteride ..."

4. Benign Prostatic Hyperplasia: Diagnosis and Treatment: Clinical Practice by DIANE Publishing Company (1995)
"A double-blind, controlled, clinical trial of spironolactone for benign prostatic hypertrophy. Br J Surg 1971;58(7):485-9. Champault G, Pate! ..."

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