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Definition of Spirem
1. spireme [n -S] - See also: spireme
Medical Definition of Spirem
1. Spireme Term formerly applied to the first stage of mitosis (prophase) when extended chromosome filaments have the appearance of a loose ball of yarn, on the incorrect supposition that the filaments were continuous and later broke apart to form individual chromosomes. Origin: G. Speirema, a coil 1 (05 Mar 2000)