Definition of Sphingosine

1. Noun. (biochemistry) An unsaturated aliphatic amino alcohol associated with the lipids of brain tissue ¹

¹ Source: wiktionary.com

Definition of Sphingosine

1. [n -S]

Medical Definition of Sphingosine

1. Long chain amino alcohol that bears an approximate similarity to glycerol with a hydrophobic chain attached to the 3 carbon. Forms the class of sphingolipids when it carries an acyl group joined by an amide link to the nitrogen. Forms sphingomyelin when phosphoryl choline is attached to the 1 hydroxyl group. Gives rise to the cerebroside and ganglioside classes of glycolipids when oligosaccharides are attached to the 1 hydroxyl group. Not found in the free form. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

Lexicographical Neighbors of Sphingosine

sphingoids
sphingol
sphingolipid
sphingolipid ceramide N-deacylase
sphingolipidoses
sphingolipidosis
sphingolipids
sphingolipodystrophy
sphingomyelin
sphingomyelin deacylase
sphingomyelin lipidosis
sphingomyelin phosphodiesterase
sphingomyelinase
sphingomyelinases
sphingomyelins
sphingosine (current term)
sphingosine CoA-independent transacetylase
sphingosine N-methyltransferase
sphingosines
sphinx
sphinx moth
sphinxes
sphinxlike
sphragide
sphragides
sphragistics
sphrigosis
sphugmicks
sphygm-
sphygmic

Literary usage of Sphingosine

Below you will find example usage of this term as found in modern and/or classical literature:

1. Practical organic and bio-chemistry by Robert Henry Aders Plimmer (1920)
"sphingosine is an unsaturated compound and contains two hydroxyl groups : — C,,HM ... They are composed of the base sphingosine, galactose and a fatty acid, ..."

2. Principles of Biochemistry for Students of Medicine, Agriculture and Related by Thorburn Brailsford Robertson (1920)
"When sphingosine is heated with concentrated sulphuric acid and a sugar, it yields a purple-violet coloration. The cerebrosides, when similarly treated, ..."

3. Principles of Biochemistry for Students of Medicine, Agriculture and Related by Thorburn Brailsford Robertson (1920)
"When sphingosine is heated with concentrated sulphuric acid and a sugar, it yields a purple-violet coloration. The cerebrosides, when similarly treated, ..."

4. Text-book of Physiological Chemistry in Thirty Lectures by Emil Abderhalden (1908)
"... sphingosine, and galactose in the following proportions: ... acid 48.13 per cent, sphingosine 34.46 per cent, galactose 21.77 per cent. ..."

5. Monographic Medicine by William Robie Patten Emerson, Guido Guerrini, William Brown, Wendell Christopher Phillips, John Whitridge Williams, John Appleton Swett, Hans Günther, Mario Mariotti, Hugh Grant Rowell (1916)
"Cephalin. II. Brain-cephalin. J. Biol. Chem., Baltimore, 1916, xiii<, Jtl-o3. sphingosine. IV. Some derivatives of sphingosine and ..."

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