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Medical Definition of Single stranded conformational polymorphism
1. Technique for detecting point mutations in genes by amplifying a region of genomic DNA (using asymmetric PCR) and running the resulting product on a high quality gel. Single base substitutions can alter the secondary structure of the fragment in the gel, producing a visible shift in its mobility. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)
Lexicographical Neighbors of Single Stranded Conformational Polymorphism
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