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Definition of Signet ring
1. Noun. A ring bearing a signet.
Medical Definition of Signet ring
1. The early stage of trophozoite development of the malaria parasite in the red blood cell; the parasite cytoplasm stains blue around its circular margin, and the nucleus stains red in Romanowsky stains, while the central vacuole is clear, giving the ringlike appearance. (05 Mar 2000)