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Definition of Severe combined immunodeficiency
1. Noun. A congenital disease affecting T cells that can result from a mutation in any one of several different genes; children with it are susceptible to infectious disease; if untreated it is lethal within the first year or two of life.
Exact synonyms: Scid, Severe Combined Immunodeficiency Disease
Generic synonyms: Immunodeficiency, Monogenic Disease, Monogenic Disorder
Specialized synonyms: Ada-scid, X-linked Scid, X-scid
Generic synonyms: Immunodeficiency, Monogenic Disease, Monogenic Disorder
Specialized synonyms: Ada-scid, X-linked Scid, X-scid
Medical Definition of Severe combined immunodeficiency
1. Group of rare congenital disorders characterised by impairment of both humoral and cell-mediated immunity, leukopenia, and low or absent antibody levels. It is inherited as an x-linked or autosomal recessive defect. About half of the patients with autosomal recessive scid are deficient in the enzyme adenosine deaminase. (12 Dec 1998)
Lexicographical Neighbors of Severe Combined Immunodeficiency
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