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Definition of Serum sickness
1. Noun. A delayed allergic reaction to the injection of an antiserum caused by an antibody reaction to an antigen in the donor serum.
Definition of Serum sickness
1. Noun. An allergylike reaction to proteins in antiserum derived from animal sources. ¹
¹ Source: wiktionary.com
Medical Definition of Serum sickness
1. A hypersensitivity response (type III) to the injection of large amounts of antigen, as might happen when large amounts of antiserum are given in a passive immunisation. The effects are caused by the presence of soluble immune complexes in the tissues. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)
Lexicographical Neighbors of Serum Sickness
Literary usage of Serum sickness
Below you will find example usage of this term as found in modern and/or classical literature:
1. Preventive medicine and hygiene by Milton Joseph Rosenau (1917)
"Semm Anaphylaxis in Man, or serum sickness.—Seni in anaphylaxis in man is met
with most frequently following the use of antitoxic sera, ..."
2. Preventive Medicine and Hygiene by Milton Joseph Rosenau, George Chandler Whipple, John William Trask, Thomas William Salmon (1916)
"Serum Anaphylaxis in Man, or serum sickness.—Scrum anaphylaxis in man is met with
most frequently following the use of antitoxic sera. and has been ..."
3. The American Journal of the Medical Sciences by Southern Society for Clinical Investigation (U.S.) (1916)
"(3) The accelerated reaction or form in which the incubation of the serum sickness
falls between the immediate reaction and the ordinary reaction and comes ..."
4. Preventive Medicine and Hygiene by Milton Joseph Rosenau, George Chandler Whipple, John William Trask, Thomas William Salmon (1921)
"There is a striking resemblance between serum sickness and measles. ... Both the
incidence and the severity of serum sickness are proportional to the amount ..."
5. Veterinary Bacteriology: A Treatise on the Bacteria, Yeasts, Molds, and by Robert Earle Buchanan (1911)
"The anaphylactic explanation of serum sickness in man has already been discussed.
Several cases are on record where injection of diphtheria antitoxin has ..."
6. An Introduction to the Study of Infection and Immunity: Including Chapters by Charles Edmund Simon (1912)
"In man the same antigen leads to those symptoms which collectively are spoken of
as serum sickness, the most common of which are the occurrence of fever, ..."
7. A Practical Text-book of Infection, Immunity, and Specific Therapy: With by John Albert Kolmer (1915)
"A concentrated serum is not so likely to produce serum sickness as whole serum,
... According to Rolleston and Ker, the frequency of serum sickness is, ..."
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