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Definition of Serum disease
1. Noun. A delayed allergic reaction to the injection of an antiserum caused by an antibody reaction to an antigen in the donor serum.
Medical Definition of Serum disease
1. A hypersensitivity response (type III) to the injection of large amounts of antigen, as might happen when large amounts of antiserum are given in a passive immunisation. The effects are caused by the presence of soluble immune complexes in the tissues. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)
Lexicographical Neighbors of Serum Disease
Literary usage of Serum disease
Below you will find example usage of this term as found in modern and/or classical literature:
1. The American Journal of the Medical Sciences by Southern Society for Clinical Investigation (U.S.) (1916)
"Apparently certain horses yield a serum which is much more likely to be attended
by serum disease than others. And finally the individual characteristics of ..."
2. The Journal of Infectious Diseases by Infectious Diseases Society of America, John Rockefeller McCormick Memorial Fund, John McCormick Institute for Infectious Diseases (1915)
"While they reject several theories which have been entertained concerning the
etiology and genesis of the serum disease, no satisfactory explanation is ..."
3. Principles of Immunology by Howard Thomas Karsner, Enrique Eduardo Ecker (1921)
"In the former group are included a relatively few cases of anaphylactic shock
and the widely- observed phenomenon called serum disease. ..."
4. The Harvey Lectures by Harvey Society of New York, New York Academy of Medicine (1917)
"Apparently, certain horses yield a serum which is much more likely to be attended
by serum disease than others. And, finally, the individual characteristics ..."
5. A Manual of Pharmacology and Its Applications to Therapeutics and Toxicology by Torald Hermann Sollmann (1922)
"serum disease.—After an incubation of eight to twelve days, ... The coagulation
time of the blood is markedly slowed during serum disease (HF Shattuck, ..."
6. A Manual of Pharmacology and Its Applications to Therapeutics and Toxicology by Torald Hermann Sollmann (1922)
"serum disease.—After an incubation of eight to twelve days, ... Relation of Serum
Disease to Antibodies.—In man, anaphylactic antibodies are not present ..."
7. A Manual of Pharmacology and Its Applications to Therapeutics and Toxicology by Torald Hermann Sollmann (1917)
"serum disease.—After an incubation of eight to twelve days, ... Relation of Serum
Disease to Antibodies.—In man, anaphylactic antibodies are not present ..."
8. A Manual of Pharmacology and Its Applications to Therapeutics and Toxicology by Torald Hermann Sollmann (1917)
"In perhaps a third of the cases, the administration of serum is followed by the
insignificant phenomena of " serum disease." Very rarely severe or fatal ..."
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