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Medical Definition of Septate junction
1. An intercellular junction found in invertebrate epithelia that is characterised by a ladder like appearance in electron micrographs. Thought to provide structural strength and to provide a barrier to diffusion of solutes through the intercellular space. Occur widely in transporting epithelia and are controversially considered analogous to tight junctions (zonula occludens). This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)