Medical Definition of Segmental glomerulosclerosis
1.
A kidney disorder that results in fibrosis and scarring in the kidney glomerulus. The cause is unknown but some cases can result from reflux nephropathy. The clinical manifestation of this kidney disorder is nephrotic syndrome.
Symptoms include weight gain, swelling, hypertension and foamy urine. High blood cholesterol and triglyceride levels are also seen with this disorder. Treatment has included the use of corticosteroids and immunosuppressives. Antihypertensive agents and diuretics may also be necessary. Over one-half will develop chronic renal failure within 10 years of diagnosis.
(27 Sep 1997)
Lexicographical Neighbors of Segmental Glomerulosclerosis
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