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Definition of Scrapie
1. Noun. A fatal disease of sheep characterized by chronic itching and loss of muscular control and progressive degeneration of the central nervous system.
Definition of Scrapie
1. Noun. A degenerative prion disease of sheep and goats that attacks the central nervous system. ¹
¹ Source: wiktionary.com
Definition of Scrapie
1. a disease of sheep [n -S]
Medical Definition of Scrapie
1. A chronic neurological disease of sheep and goats, similar to other spongiform encephalopathies and much used as a model for studying the diseases. Controversy still surrounds the nature of the transmissible agent slow viruses are proposed by some workers, prions by an increasing number of others. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)
Literary usage of Scrapie
Below you will find example usage of this term as found in modern and/or classical literature:
1. The Journal of Comparative Pathology and Therapeutics (1888)
"It has not, as yet, been possible to demonstrate unequivocally sheep-to- sheep
contagion because of lack of a group of sheep susceptible to scrapie which ..."
2. The Journal of Comparative Pathology and Therapeutics (1888)
"Unless otherwise stated, the "strain" of scrapie used was that described ...
RESULTS Further Intracerebral Passage of scrapie through Goats Pattison et al. ..."
3. Potential Transmission of Spongiform Encephalopathies to Humans: The Food edited by Christopher Shays (1998)
"The scrapie agent shows marked resistance to radiation and survives high
temperatures, although 100°C kills 99% of the scrapie agent in 1 minute with ..."
4. Novel Systems for the Study of Human Disease: From Basic Research to by OECD Staff, (Paris) Organisation for Economic Co-ope (1998)
"JEFFREY, M., CM GOODSIR, MEBRUCE, PA MCBRIDE, N. FOWLER, and JRSCOTT (1994), "Murine
scrapie-infected neurons in vivo release excess prion protein into the ..."
5. Mammalian Models for Research on Aging by Institute Of Laboratory Animal Resources, Bennett J. Cohen, National Research Council Staff (1981)
"Specific scrapie agents in certain strains of mice can induce amyloid and
neuritic (senile) ... scrapie is a naturally occurring disease of sheep and goats, ..."
6. Animal Health at the Crossroads: Preventing, Detecting, And Diagnosing by National Research Council (U. S.) (2005)
"scrapie is a degenerative and eventually fatal disease that targets the central
nervous systems of sheep and goats. These researchers found that lymphoid ..."
7. The Pathology and Differential Diagnosis of Infectious Diseases of Animals by Veranus Alva Moore (1916)
"M'Gowan (Investigation into the disease of sheep called "scrapie," 1914) ...
"Pruritis (or itching), the chief symptom in scrapie, can be reproduced in ..."
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