Medical Definition of Rolling circle mechanism

1. A mechanism of DNA replication in many viral DNAs, in bacterial f factors during mating and of certain DNAs in gene amplification in eukaryotes. DNA synthesis starts with a cut in the + strand at the replication origin, the 5' end rolls out and replication starts at the 3' side of the cut around the intact circular DNA strand. Replication of the 5' end (tail) takes place by the formation of Okazaki fragments. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

Lexicographical Neighbors of Rolling Circle Mechanism

roller skating
roller towel
Rolleston's rule
Rollet's stroma
rollick
rollicked
rollicking
rollickingly
rollicks
rollicky
rolling
rolling
rolling-pin
rollings
rolling circle
rolling circle mechanism (current term)
rolling hitch
rolling mill
rolling paper
rolling pin
rolling stock
rolling wave
rollmop
rollmops
Rollo
rollock
rollocks
rollout
rollouts
rollover

Other Resources:

Search for Rolling circle mechanism on Dictionary.com!Search for Rolling circle mechanism on Thesaurus.com!Search for Rolling circle mechanism on Google!Search for Rolling circle mechanism on Wikipedia!

Search