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Medical Definition of Rebound phenomenon
1. Generally, any phenomenon in which a variable that has been displaced from its normal state by a disturbing influence temporarily deviates from normal in the opposite direction when the disturbing influence is suddenly removed, before finally stabilizing at its normal state, i.e., a phenomenon involving undershoot; e.g., the subsequent hypoglycaemia that may follow injection of glucose, because the initial hyperglycaemia caused excessive secretion of insulin. Synonym: Stewart-Holmes sign (05 Mar 2000)