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Definition of Quinacrine hydrochloride
1. Noun. A drug (trade name Atabrine) used to treat certain worm infestations and once used to treat malaria.
Exact synonyms: Atabrine, Mepacrine, Quinacrine
Generic synonyms: Antimalarial, Antimalarial Drug, Anthelminthic, Anthelmintic, Helminthic, Vermifuge
Language type: Trade Name
Generic synonyms: Antimalarial, Antimalarial Drug, Anthelminthic, Anthelmintic, Helminthic, Vermifuge
Language type: Trade Name
Medical Definition of Quinacrine hydrochloride
1. An acridine derivative, C23H30ClN3O-2HCl-2H2O, used as an antimalarial that destroys the trophozoites of Plasmodium vivax and P. Falciparum, but does not affect the gametocytes, sporozoites, or exoerythrocytic stage of parasites; also used as an anthelmintic. As a dihydrochloride, it is used as a stain in cytogenetics to demonstrate Y chromatin by fluorescent microscopy. Quinacrine hydrochloride intercalates with DNA and also uncouples oxidative and photophosphorylation. Synonym: atebrine hydrochloride, mepacrine hydrochloride. (05 Mar 2000)