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Definition of Preclinical phase
1. Noun. A laboratory test of a new drug or a new invasive medical device on animal subjects; conducted to gather evidence justifying a clinical trial.
Lexicographical Neighbors of Preclinical Phase
Literary usage of Preclinical phase
Below you will find example usage of this term as found in modern and/or classical literature:
1. Living Longer, Growing Stronger: The Vital Role of Geriatric Medicine edited by Charles E. Grassley (1998)
"In the preclinical phase of medical school, typically the first two years, basic
scientists discuss issues of aging and senescence as these concepts apply ..."
2. Diabetes in America by Ronald Aubert (1996)
"Source: Reference 9 THE preclinical phase OF NIDDM The high prevalence of
undiagnosed NIDDM indicates there must be a considerable preclinical phase for the ..."
3. Meeting the Challenge: U. S. Industry Faces the 21st Century: The U. S by Jon Paugh (1998)
"... phases I through III and projects under FDA review.12 Approximately 700 drugs
are in early development stages (the research and preclinical phase). ..."
4. Risk Assessment for Neurobehavioral Toxicity edited by Bernard Weiss, Jurg Elsner (1997)
"... effects with the aim of enabling the investigators to assess/quantify risks
at therapeutic dose levels. During the preclinical phase of pharmaceutical ..."
5. Review Of Fluoride: Benefits And Risks. Report Of The Ad Hoc Subcommittee On by DIANE Publishing Company (1992)
"... 1)OOQ preclinical phase 3500 - 5500 asymptomatic; slight radiographically-detectable
increases in bone mass Clinical Phase I 6000 - 7000 sporadic pain; ..."
6. Potential Transmission of Spongiform Encephalopathies to Humans: The Food edited by Christopher Shays (1998)
"... well as mutation-positive but still healthy members of CJD families to examine
the infectious status of blood during the preclinical phase of disease. ..."
7. Optimality: The Second Erich L. Lehmann Symposium by Javier Rojo (2006)
"In cancer screening programs, whether the pathological changes of a patient in
the preclinical phase can be discovered depends very much on the phase of the ..."
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