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Medical Definition of Polysialic acid
1. Potential regulator of cell cell interactions. Polysialic acid chains in glycoproteins, for example when covalently associated with NCAM, have negative regulatory effects on cell cell contact. The low PSA form of NCAM is thought to promote cell cell contact and enhance fasiculation whereas NCAM with a high PSA content is thought to prevent close membrane membrane apposition. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)
Lexicographical Neighbors of Polysialic Acid
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