|
Medical Definition of Polyposis coli
1. Hereditary disorder (Mendelian dominant) characterised by the development of hundreds of adenomatous polyps in the large intestine, which show a tendency to progress to malignancy. The APC gene has also been implicated in a chromosome 5 gastric and pancreatic cancer. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)