Lexic.us

Definition of Polymyxin

1. Noun. Any of several toxic antibiotics obtained from a particular soil bacterium.

Definition of Polymyxin

1. Noun. Any of several toxic antibiotics, derived from the soil bacterium ''Bacillus polymyxa'', used to treat infections by gram-negative bacteria ¹

¹ Source: wiktionary.com

Definition of Polymyxin

1. [n -S]

Medical Definition of Polymyxin

1. Basic polypeptide antibiotic group obtained from bacillus polymyxa. They affect the cell membrane by detergent action and may cause neuromuscular and kidney damage. at least eleven different members of the polymyxin group have been identified, each designated by a letter. Pharmacological action: antibiotics, peptide. (12 Dec 1998)

Lexicographical Neighbors of Polymyxin

Literary usage of Polymyxin

Below you will find example usage of this term as found in modern and/or classical literature:

1. Code of Federal Regulations by Food and Drug Administration (FDA) Staff (2005)
"(5) Bacitracin zinc-neomycin sulfate- polymyxin B sulfate ointment containing, in each gram, in a suitable ointment base the following: (i) 400 units of ..."

2. A Lifelong Passion: Nicholas and Alexandra: Their Own Story by Andrei Maylunas (2005)
"D-Sphingosine, an inhibitor of protein kinase C, was able to partially block the phorbol ester- induced increase in toxin binding while polymyxin B, ..."

3. Reviews in Environmental Health (1998): Toxicological Defense Mechanics edited by Gary E. R. Hook, George W. Lucier (2000)
"Bronchitis also has been successfully induced in guinea pigs by intranasal administration of polymyxin B sulfate (a mast cell-degranulating agent) at a ..."

4. Proceedings of the Society for Experimental Biology and Medicine (1903)
"... polymyxin B, coli- may interact with the protoplast ne and through perturbation, acti- membrane-associated autolytic sys- rough the removal of LTA (14). ..."

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