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Medical Definition of Polycystic disease of kidneys
1. A progressive disease characterised by formation of multiple cysts of varying size scattered diffusely throughout both kidney's, resulting in compression and destruction of kidney parenchyma, usually with hypertension, gross haematuria, and uraemia; there are two major types: 1) with onset in infancy or early childhood, usually with autosomal recessive inheritance; 2) with onset in adulthood, with autosomal dominant inheritance. Synonym: polycystic disease of kidneys. (05 Mar 2000)