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Definition of Piss off
1. Verb. (idiomatic intransitive vulgar colloquial UK Canada) To leave, to go away. (defdate from mid-20th c.) ¹
2. Verb. (idiomatic transitive vulgar colloquial) To annoy, anger ¹
3. Interjection. (UK Canada idiomatic vulgar colloquial dismissal) (non-gloss definition Used to tell someone to go away.) ¹
¹ Source: wiktionary.com