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Medical Definition of Pigmented retinal epithelium
1. Layer of unusual phagocytic epithelial cells lying below the photoreceptors of the vertebrate eye. The dorsal surface of the PRE cell is closely apposed to the ends of the rods and as discs are shed from the rod outer segment they are internalised and digested by the PRE. Do not have desmosomes or cytokeratins in some species. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)