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Medical Definition of Piebald skin
1. Patchy absence of the pigment of scalp hair, giving a streaked appearance; patches of vitiligo may be present in other areas sue to absence of melanocytes; often transmitted as an autosomal dominant trait and may be associated with neurological defects or eye changes . Compare: Waardenburg syndrome. Synonym: piebald skin, piebaldism. (05 Mar 2000)