Medical Definition of Phosphoribosyltransferase

1. One of a group of enzymes (EC sub-subclass 2.4.2, pentosyltransferases) that transfers d-ribose 5-phosphate from 5-phospho-alpha-d-ribosyl pyrophosphate to a purine, pyrimidine, or pyridine acceptor, forming a 5'-nucleotide and inorganic pyrophosphate, or d-ribose from d-ribosyl phosphate to a base, forming a nucleoside, or similar pentose transfers; important in nucleotide biosynthesis. Specific phosphoribosyltransferases are preceded by the name of the acceptor base, e.g., uracil phosphoribosyltransferase (i.e., uracil + PRPP &dblarr; UMP + pyrophosphate). (05 Mar 2000)

Lexicographical Neighbors of Phosphoribosyltransferase

phosphorescent
phosphorescent
phosphoresces
phosphorescing
phosphorhidrosis
phosphori
phosphoriboisomerase
phosphoribomutase
phosphoribosylaminoimidazolecarboxamide formyltransferase
phosphoribosylaminopyrimidine deaminase
phosphoribosylaminopyrimidine reductase
phosphoribosylanthranilate isomerase
phosphoribosylanthranilate isomerase-indoleglycerol-phosphate synthase
phosphoribosylformylglycinamidine synthetase
phosphoribosylglycineamide synthetase
phosphoribosyltransferase (current term)
phosphoribosyl pyrophosphate
phosphoribulokinase
phosphoribulose epimerase
phosphoric
phosphoric
phosphorical
phosphoric acid
phosphoric acid
phosphoric acids
phosphoric acid esters
phosphoric diester hydrolases
phosphoric monoester hydrolases
phosphoridrosis
phosphorised

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