Medical Definition of Phosphomannose
1.
Mannose derivative formed by phosphorylation in the Golgi complex of certain mannose residues on N glycan chains of lysosomal enzymes.
Believed to function as targetting signal that causes entry of these enzymes to the lysosomes. The receptor (215 kD) is enriched in specialised pre lysosomes.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
An enzyme that catalyses the reversible isomerization of d-mannose-6-phosphate to form d-fructose-6-phosphate, an important step in glycolysis.
Chemical name: D-Mannose-6-phosphate ketol isomerase
Registry number: EC 5.3.1.8
(12 Dec 1998)
Receptors in Golgi apparatus to which newly synthesised proteins that are destined to enter lysosomes bind.
(05 Mar 2000)
Involved in biosynthesis of mannitol in celery
Registry number: EC 1.1.1.224
Synonym: manp reductase
(26 Jun 1999)
Lexicographical Neighbors of Phosphomannose
Other Resources: