|
Definition of Phosphoglyceromutase
1. Noun. (biochemistry) An enzyme involved in glycolysis that catalyzes the internal transfer of a phosphate group from C-3 to C-2, resulting in the conversion of 3-phosphoglycerate to 2-phosphoglycerate through a 2,3-bisphosphoglycerate intermediate. ¹
¹ Source: wiktionary.com
Medical Definition of Phosphoglyceromutase
1. An isomerizing enzyme catalyzing the reversible interconversion of 2-phosphoglycerate and 3-phosphoglycerate with 2,3-bisphosphoglycerate present as a cofactor; a deficiency of this enzyme, which plays a role in glycolysis, is an inherited disorder that results in an intolerance for strenuous exercise. (05 Mar 2000)