Medical Definition of Phosphatidylserine

1. The condensation product of phosphatidic acid and serine, found in biomembranes. It is an important minor species of phospholipid in membranes. Serine is attached to phosphatidic acid by a phosphodiester linkage. Complete hydrolysis yields 1 mole of glycerol, phosphoric acid and serine and 2 moles of fatty acids. Synthesis is from phosphatidylethanolamine by exchange of ethanolamine for serine. Distribution is asymmetric, as the molecule is only present on the cytoplasmic side of cellular membranes. It is negatively charged at physiological pH and interacts with divalent cations, involved in calcium dependent interactions of proteins with membranes (e.g. Protein kinase C). See: cephalin. (20 Sep 2002)

Lexicographical Neighbors of Phosphatidylserine

phosphatidylethanolamine cytidylyltransferase
phosphatidylethanolamine N-acyltransferase
phosphatidylglycerol
phosphatidylglycerols
phosphatidylglycerol - membrane-oligosaccharide glycerophosphotransferase
phosphatidylglycerol glyceryl transferase
phosphatidylinositol
phosphatidylinositol-3-phosphatase
phosphatidylinositol-ceramide phosphoinositol transferase
phosphatidylinositols
phosphatidylinositol 4-phosphate
phosphatidylinositol 4-phosphate phosphatase
phosphatidylinositol phosphates
phosphatidylinositol synthase
phosphatidyls
phosphatidylserine (current term)
phosphatization
phosphatize
phosphatized
phosphatizes
phosphatizing
phosphaturia
phosphaturia
phosphaturias
phosphene
phosphene
phosphenes
phosphid
phosphide
phosphide

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