Lexic.us

Definition of Phenothiazine

1. Noun. A compound used primarily in veterinary medicine to rid farm animals of internal parasites.

Definition of Phenothiazine

1. Noun. (organic compound) A polycyclic heterocycle consisting of two benzene rings fused to one of thiazine; thiodiphenylamine, dibenzothiazine ¹

2. Noun. (medicine) Any of a family of pharmaceuticals, derived from this compound, used to treat schizophrenia etc. ¹

¹ Source: wiktionary.com

Definition of Phenothiazine

1. [n -S]

Medical Definition of Phenothiazine

1. A group of tranquilising medications with antipsychotic action, thought to act by blocking dopaminergic transmission in the brain. They are used to treat mental, nervous and emotional disorders. Examples include: chlorpromazine, fluphenazine, mesoridazine, perphenazine, prochlorperazine, promazine, thioridazine, trifluoperazine, thiopropazate and triflupromazine. Trifluoperazine binds to and inhibits calmodulin and has been used experimentally to block calcium or calmodulin controlled reactions. (29 Sep 1997)

Lexicographical Neighbors of Phenothiazine

Literary usage of Phenothiazine

Below you will find example usage of this term as found in modern and/or classical literature:

1. Code of Federal Regulations, Title 21, Food and Drugs, Pt. 800-1299, Revised by Food and Drug Administration (FDA) Staff (2005)
"A phenothiazine test system is a device intended to measure any of the drugs of the phenothiazine class in human specimens. Measurements obtained by this ..."

2. Code of Federal Regulations by Food and Drug Administration (FDA) Staff (2005)
"NOTE: Not for use with organophosphates and/or procaine hydrochloride, as phenothiazine may potentiate the toxicity of organophosphates and the activity of ..."

3. Value of Psychiatric Treatment: Its Efficacy in Severe Mental Disorders edited by Samuel J. Keith (1996)
"phenothiazine treatment in acute schizophrenia. Arch. Gen. Psychiatry 10:246-261, 1964. O'Brien, CP; Hamm, KB; Ray, BA; Pierce, JF; Luborsky, L; and Mintz, ..."

4. The Lasting Salute: Civil & Military Funerals 1921-1969 by B. C. Mossman, M. W. Stark (1995)
"Methotrimeprazine is a phenothiazine that has analgesic properties. ... This phenothiazine analgesic lacks opioid-inhibitory effects on gut motility and ..."

5. Partnerships and Collaboration as Competitiveness Tools: Hearing Before the by United States, Congress, House (1993)
"... phenothiazine antipsychotic and tricyclic antidepressant Combination phenothiazine antipsychotic and tricyclic antidepressant Combination phenothiazine, ..."

6. Science by American Association for the Advancement of Science (1883)
"The history of psychoactive drugs is replete with such examples. phenothiazine was initially used as a urinary antiseptic ..."

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