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Medical Definition of Peripheral blood stem cell transplantation
1. A procedure that is similar to bone marrow transplantation. Doctors remove healthy immature cells (stem cells) from a patient's blood and store them before the patient receives high-dose chemotherapy and possibly radiation therapy to destroy the leukaemia cells. The stem cells are then returned to the patient, where they can produce new blood cells to replace cells destroyed by the treatment. (12 Dec 1998)