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Medical Definition of Paramyloidosis
1. 1. Deposition in tissues of an amyloid-like protein resembling light chains of immunoglobulins in primary amyloidosis or (particularly) in atypical amyloidosis of multiple myeloma. 2. Various hereditary amyloidoses (Portuguese amyloidosis, Indiana amyloidosis) characterised by progressive hypertrophic polyneuritis with sensory changes, ataxia, paresis, and muscle atrophy due to amyloid deposits in peripheral and visceral nerves. (05 Mar 2000)