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Medical Definition of Nonpitting oedema
1. Swelling of subcutaneous tissues which cannot be indented by compression easily. Usually due to metabolic abnormality, such as increased glycosaminoglycan content, like that which occurs in Graves' disease (pretibial myxoedema) or in early phase of scleroderma. Synonym: brawny oedema. (05 Mar 2000)