Medical Definition of Nogalamycin
1.
An antineoplastic agent from a streptomyces nogalater variant. It is a cytolytic antibiotic that inhibits DNA-dependent RNA synthesis by binding to DNA and has some antibacterial action.
Pharmacological action: antibiotics, anthracycline, intercalating agents, nucleic acid synthesis inhibitors.
Chemical name: 2,6-Epoxy-2H-naphthaceno(1,2-b)oxocin-14-carboxylic acid, 11-((6-deoxy-3-C-methyl-2,3,4-tri-O-methyl-alpha-L-mannopyranosyl)oxy)-4-(dimethylamino)-3,4,5,6,9,11,12,13,14,16-decahydro-3,5,8,10,13-pentahydroxy-6,13-dimethyl-9,16-dioxo-, methyl ester, (2R-(2alpha,3beta,4alpha,5beta,6alpha,11beta,13alpha,14alpha))-
(12 Dec 1998)
Lexicographical Neighbors of Nogalamycin
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