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Definition of Neuromuscular blocking agent
1. Noun. A substance that interferes with the neural transmission between motor neurons and skeletal muscles.
Generic synonyms: Blocker, Blocking Agent
Specialized synonyms: Flaxedil, Gallamine, Curare, Tubocurarine
Specialized synonyms: Flaxedil, Gallamine, Curare, Tubocurarine
Medical Definition of Neuromuscular blocking agent
1. A group of drugs that prevent motor nerve endings from exciting skeletal muscle. They act either by competing for the neurotransmitter, acetylcholine, (like D-tubocurarine, mivacurium and pancuronium), or by first stimulating the postjunctional muscle membrane and subsequently desensitizing the muscle endplates to the acetylcholine (like succinylcholine or decamethonium); used in surgery to produce paralysis and facilitate manipulation of muscles. (05 Mar 2000)