Lexic.us

Definition of Myasthenia gravis

1. Noun. A chronic progressive disease characterized by chronic fatigue and muscular weakness (especially in the face and neck); caused by a deficiency of acetylcholine at the neuromuscular junctions.

Medical Definition of Myasthenia gravis

1. The characteristic feature of the disease is easy fatigue of certain voluntary muscle groups on repeated use. Muscles of the face or upper trunk are especially likely to be affected. In most and perhaps all cases due to the development of autoantibodies against the acetylcholine receptor in neuromuscular junctions. Immunisation of mice or rats with this receptor protein leads to a disease with the features of myasthenia. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

Lexicographical Neighbors of Myasthenia Gravis

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