Medical Definition of Monolayering of cell
1.
| Tendency of animal tissue cells growing on solid surfaces to cover the surface with a complete layer only one cell thick, before growing on top of each other. This nonrandom distribution is generated by contact inhibition of locomotion, a phenomenon in which colliding cells change direction rather than move over one another. Of the theories why some (but by no means all) types of cells stop growing when a monolayer is formed, present evidence favours limitation by supply of growth factors from the medium, rather than any inhibitory effect of contact on growth.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
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Lexicographical Neighbors of Monolayering Of Cell
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