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Definition of Mithridatism
1. Noun. The development of immunity to a poison by gradual ingestion of successively greater amounts. ¹
¹ Source: wiktionary.com
Medical Definition of Mithridatism
1. Immunity against the action of a poison produced by small and gradually increasing doses of the same. Origin: Mithridates, King of Pontus (132-63 B.C.), supposedly an unsuccessful suicide (by poison) because of repeated small doses taken to become invulnerable to assassination by poison (05 Mar 2000)