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Medical Definition of Minor histocompatibility loci
1. Genetic loci responsible for the encoding of histocompatibility antigens other than those encoded by the major histocompatibility complex. The antigens encoded by these genes are often responsible for graft rejection in cases where histocompatibility has been established by standard tests. The location of some of these loci on the x and y chromosomes explains why grafts from males to females may be rejected while grafts from females to males are accepted. In the mouse roughly 30 minor histocompatibility loci have been recognised, comprising more than 500 genes. (12 Dec 1998)
Lexicographical Neighbors of Minor Histocompatibility Loci
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