Lexic.us

Definition of Mifepristone

1. Noun. An abortion-inducing drug (trade name RU_486) developed in France; when taken during the first five weeks of pregnancy it blocks the action of progesterone so that the uterus sloughs off the embryo.

Definition of Mifepristone

1. Noun. (steroid drug) A steroid pharmaceutical used to induce abortion, or as an emergency contraceptive. ¹

¹ Source: wiktionary.com

Definition of Mifepristone

1. [n -S]

Medical Definition of Mifepristone

1. A progestational and glucocorticoid hormone antagonist. Its inhibition of progesterone induces bleeding during the luteal phase and in early pregnancy by releasing endogenous prostaglandins from the endometrium or decidua. As a glucocorticoid receptor antagonist, the drug has been used to treat hypercortisolism in patients with nonpituitary cushing's syndrome. Pharmacological action: abortifacient agents, steroidal, contraceptives, oral, synthetic, contraceptives, postcoital, synthetic, hormone antagonists, luteolytic agents, menstruation-inducing agents. Chemical name: Estra-4,9-dien-3-one, 11-(4-(dimethylamino)phenyl)-17-hydroxy-17-(1-propynyl)-, (11beta,17beta)- (12 Dec 1998)

Lexicographical Neighbors of Mifepristone

Literary usage of Mifepristone

Below you will find example usage of this term as found in modern and/or classical literature:

1. Food and Drug Administration: Decision Process to Deny Initial Application by Marcia Crosse (2006)
"... and the approval of mifepristone for the termination of early pregnancy in ... mifepristone, there was no disagreement between high-level management and ..."

2. Guide to Clinical Preventive Services: Report of the U. S. Preventive by DIANE Publishing Company (1996)
"mifepristone (RU 486) compared with high-dose estrogen and progestogen for emergency postcoital contraception. N Engl J Med 1992:327:1041-1044. 49. ..."

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