1. Noun. A basic heparin-binding growth factor of low molecular weight ¹
¹ Source: wiktionary.com
Medical Definition of Midkine
1. Heparin binding growth factor (13 kD) of the TGF superfamily, has 50% sequence identity with Heparin Binding Growth Associated Molecule (HB GAM). Structurally unrelated to FGF. Midkine was originally described as associated with tooth morphogenesis induced by epithelial mesenchyme interactions. Nucleolin binds midkine.
This entry appears with permission from the Dictionary of Cell and Molecular Biology
(11 Mar 2008)
