Definition of Methotrexate

1. Noun. Toxic antimetabolite that limits cellular reproduction by acting as an antagonist to folic acid; used to treat certain cancers and psoriasis and rheumatoid arthritis.

Exact synonyms: Amethopterin, Methotrexate Sodium
Generic synonyms: Antimetabolite, Immune Suppressant Drug, Immunosuppressant, Immunosuppressive, Immunosuppressive Drug, Immunosuppressor

Definition of Methotrexate

1. Noun. (medicine) An antimetabolite and antifolate drug used in treatment of cancer and autoimmune diseases. ¹

¹ Source: wiktionary.com

Definition of Methotrexate

1. [n -S]

Medical Definition of Methotrexate

1. Analogue of dihydrofolate. Inhibits dihydrofolate reductase and kills rapidly growing cells. Therapeutic agent for leukaemias, but has a low therapeutic ratio. This entry appears with permission from the Dictionary of Cell and Molecular Biology (11 Mar 2008)

Lexicographical Neighbors of Methotrexate

methodology
methods
methohexital
methohexital sodium
methohexitone
methol
methomyl
methonium compounds
methophenazine
methopholine
methoprene
methopterin
methorphan
methorphinan
methoserpidine
methotrexate (current term)
methotrexate sodium
methotrexates
methotrimeprazine
methought
methoxamine
methoxamine hydrochloride
methoxatin
methoxetamine
methoxide
methoxides
methoxsalen
methoxy
methoxy-
methoxyamination

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